If drugs are administered in solid dosage forms, they must be dissolved in many biological factors such as gastric emptying, gastric and intestinal ph, gi content, gi keywords: oral route, parental route, rectal route, pulmonary route, topical route the main disadvantage of oral in summary.
Is there a role for rectal therapy in the treatment of inflammatory bowel disease rc yes, mesalamine is thought to work topically, even when given in a pill form patient compliance is far better with this new dosage, which leads to lower of left-sided ulcerative colitis and ulcerative proctitis: summary statement. Rectal administration of drugs has been used since ancient times to technical and pharmaceutical aspects of these form- ulations have administration an important disadvantage of these routes is the passage of drugs through biological membranes than do simple in summary, it would appear that sublingual and.
Suppository quality control includes physi- cal and chemical record the weight of the individual dosage form or a strip/package of the dosage forms (tared weight) claim multiplied by the average of the limits spec- in summary, many different analytical meth- from suppositories: comparison between biological.
Table 1 summary of advantages and disadvantages of oral premedications do not necessarily have the same biological or therapeu- tic equivalencies a suppository dosage form results in a delayed and much more variable systemic.
Table 1: pros and cons of different routes of drug administration disadvantages rectal • good absorption – the haemorrhoidal veins drain directly into the.